Thank you for your question. We can ensure that you eating durian and drinking Coca-Cola at the same time do no harm to your health. Related Items FAQ More On Journey Where is the secret formula of Coca-Cola kept? How much caffeine does Coca-Cola contain? Can you use Coca-Cola to clean a toilet? Is it true that you can die from eating Mentos and drinking Coke at the same time? How many calories are there in a 320ml can of Coca‑Cola Classic?