Thank you for your question. We can ensure that you eating durian and drinking Coca-Cola at the same time do no harm to your health. Related Items FAQ More On Journey Can I use Coca‑Cola as a household cleaner? Are there any additives in Coca‑Cola? Can I drink Coca‑Cola if I have diabetes? How many calories are there in a 320ml can of Coca‑Cola Classic? How much sugar is in Coca‑Cola Zero Sugar?